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MRI no effect on reoperation rates
Posted by: Anonymous User (IP Logged)
Date: February 19, 2010 08:51PM

ADDITION of magnetic resonance imaging (MRI) scans to conventional triple assessment techniques for diagnosis of breast cancer has no effect on the reoperation rate.

This is the conclusion of a study, “Comice”, written by Lindsay Turnbull, university of Hull and Hull royal infirmary, UK, and colleagues.

This randomised controlled study took place in 45 UK centres, recruiting 1,623 women aged 18 years or older with biopsy-proven primary breast cancer - scheduled for surgery to remove their tumours after triple assessment.

Patients were randomly assigned to receive either MRI (816) or no further imaging (807).

The primary endpoint was the proportion of patients undergoing a repeat operation or further mastectomy within six months of randomisation, or a pathologically avoidable mastectomy at initial operation.

The researchers found that addition of MRI to conventional triple assessment was not significantly associated with reduced a reoperation rate, with 153 (19%) needing reoperation in the MRI group versus 156 (19%) in the no MRI group.

The authors said: “In the analysis, we identified no difference in health-related quality of life between groups 12 months after initial surgery.

“However, in terms of total costs, results suggested a difference between the two trial groups, with the MRI group costing more than the no MRI group, although the difference was not statistically significant.

“In view of the similar clinical and health related quality-of-life outcomes of patients in both groups, we conclude that the addition of MRI to the conventional triple assessment might result in extra use of resources at the initial surgery period, with few or no benefits to saving resources or health outcomes, and the additional burden on patients to attend extra hospital visits.”

They concluded: “Our results have important implications in routine clinical practice for the appropriate use of health-service resources and patient burden on health services.

“MRI is an expensive procedure. Because surgical use of MRI data to direct wide local excision is similar worldwide, we believe that our findings are generalisable to all healthcare providers, and show that MRI might not be necessary in this population of patients in terms of reduction of reoperation rates.”

In an accompanying comment, Elizabeth Morris, Sloan-Kettering cancer center and Weill Cornell medical college, New York, US, said: “It is too early to completely dispense with preoperative breast MRI.

“Importantly, the study has shown that preoperative breast MRI might not be for all women and that routine breast MRI in the evaluation of early breast cancer, as managed by those participating in this study, does not decrease reoperation rates.”

Re: MRI no effect on reoperation rates
Posted by: Hargereade (IP Logged)
Date: December 22, 2018 12:09PM


Re: MRI no effect on reoperation rates
Posted by: TristanTrundle (IP Logged)
Date: September 01, 2019 09:28AM


Re: MRI no effect on reoperation rates
Posted by: TristanTrundle (IP Logged)
Date: September 01, 2019 09:28AM




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